Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS30003053HIVENSG00000105329.11protein_codingTGFB1NoNo7040P01137
TVIS30003054HIVENSG00000105329.11protein_codingTGFB1NoNo7040P01137
TVIS30007508HIVENSG00000105329.11protein_codingTGFB1NoNo7040P01137
TVIS30019487HIVENSG00000105329.11protein_codingTGFB1NoNo7040P01137
TVIS30048701HIVENSG00000105329.11protein_codingTGFB1NoNo7040P01137
TVIS30048702HIVENSG00000105329.11protein_codingTGFB1NoNo7040P01137
TVIS30048703HIVENSG00000105329.11protein_codingTGFB1NoNo7040P01137
TVIS20027277HPVENSG00000105329.11protein_codingTGFB1NoNo7040P01137
TVIS44030110HTLV-1ENSG00000105329.11protein_codingTGFB1NoNo7040P01137
TCGA Plot Options
Drug Information
GeneTGFB1
DrugBank IDDB00070
Drug NameHyaluronidase (ovine)
Target IDBE0000984
UniProt IDP01137
Regulation Typeinhibitor
PubMed IDs11327694; 7648625; 9435505; 9850732
CitationsChang NS: Hyaluronidase activation of c-Jun N-terminal kinase is necessary for protection of L929 fibrosarcoma cells from staurosporine-mediated cell death. Biochem Biophys Res Commun. 2001 May 4;283(2):278-86.@@Locci P, Marinucci L, Lilli C, Martinese D, Becchetti E: Transforming growth factor beta 1-hyaluronic acid interaction. Cell Tissue Res. 1995 Aug;281(2):317-24.@@Chang NS: Hyaluronidase enhancement of TNF-mediated cell death is reversed by TGF-beta 1. Am J Physiol. 1997 Dec;273(6 Pt 1):C1987-94.@@Chang NS: Transforming growth factor-beta protection of cancer cells against tumor necrosis factor cytotoxicity is counteracted by hyaluronidase (review). Int J Mol Med. 1998 Dec;2(6):653-9.
GroupsApproved; Investigational
Direct ClassificationPeptides
SMILES
Pathways
PharmGKBPA164745713
ChEMBLCHEMBL1201636