| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10040912 | HBV | ENSG00000077097.17 | protein_coding | TOP2B | No | No | 7155 | Q02880 |
| TVIS30003476 | HIV | ENSG00000077097.17 | protein_coding | TOP2B | No | No | 7155 | Q02880 |
| TVIS30008273 | HIV | ENSG00000077097.17 | protein_coding | TOP2B | No | No | 7155 | Q02880 |
| TVIS30056472 | HIV | ENSG00000077097.17 | protein_coding | TOP2B | No | No | 7155 | Q02880 |
| TVIS30056473 | HIV | ENSG00000077097.17 | protein_coding | TOP2B | No | No | 7155 | Q02880 |
| TVIS30056474 | HIV | ENSG00000077097.17 | protein_coding | TOP2B | No | No | 7155 | Q02880 |
| TVIS30056475 | HIV | ENSG00000077097.17 | protein_coding | TOP2B | No | No | 7155 | Q02880 |
| TVIS20032084 | HPV | ENSG00000077097.17 | protein_coding | TOP2B | No | No | 7155 | Q02880 |
| TVIS20036520 | HPV | ENSG00000077097.17 | protein_coding | TOP2B | No | No | 7155 | Q02880 |
| TVIS44008532 | HTLV-1 | ENSG00000077097.17 | protein_coding | TOP2B | No | No | 7155 | Q02880 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | TOP2B |
|---|---|
| DrugBank ID | DB00380 |
| Drug Name | Dexrazoxane |
| Target ID | BE0002425 |
| UniProt ID | Q02880 |
| Regulation Type | |
| PubMed IDs | 17139284; 17016423; 10592235 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. |
| Groups | Approved; Withdrawn |
| Direct Classification | Alpha amino acids and derivatives |
| SMILES | C[C@@H](CN1CC(=O)NC(=O)C1)N1CC(=O)NC(=O)C1 |
| Pathways | |
| PharmGKB | PA449259 |
| ChEMBL | CHEMBL1738 |
