Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS30082858HIVENSG00000104321.11protein_codingTRPA1NoNo8989O75762
TVIS20063188HPVENSG00000104321.11protein_codingTRPA1NoNo8989O75762
TVIS20040911HPVENSG00000104321.11protein_codingTRPA1NoNo8989O75762
TVIS44005389HTLV-1ENSG00000104321.11protein_codingTRPA1NoNo8989O75762
TCGA Plot Options
Drug Information
GeneTRPA1
DrugBank IDDB00825
Drug NameLevomenthol
Target IDBE0001122
UniProt IDO75762
Regulation Typeinducer
PubMed IDs12654248; 15931068; 16829128; 11752352
CitationsStory GM, Peier AM, Reeve AJ, Eid SR, Mosbacher J, Hricik TR, Earley TJ, Hergarden AC, Andersson DA, Hwang SW, McIntyre P, Jegla T, Bevan S, Patapoutian A: ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures. Cell. 2003 Mar 21;112(6):819-29.@@Namer B, Seifert F, Handwerker HO, Maihofner C: TRPA1 and TRPM8 activation in humans: effects of cinnamaldehyde and menthol. Neuroreport. 2005 Jun 21;16(9):955-9.@@Macpherson LJ, Hwang SW, Miyamoto T, Dubin AE, Patapoutian A, Story GM: More than cool: promiscuous relationships of menthol and other sensory compounds. Mol Cell Neurosci. 2006 Aug;32(4):335-43. Epub 2006 Jul 7.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5.
GroupsApproved
Direct ClassificationMenthane monoterpenoids
SMILESCC(C)[C@@H]1CC[C@@H](C)C[C@H]1O
Pathways
PharmGKBPA164776605
ChEMBLCHEMBL470670