| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30044536 | HIV | ENSG00000108423.16 | protein_coding | TUBD1 | No | No | 51174 | Q9UJT1 |
| TVIS30021386 | HIV | ENSG00000108423.16 | protein_coding | TUBD1 | No | No | 51174 | Q9UJT1 |
| TVIS30044537 | HIV | ENSG00000108423.16 | protein_coding | TUBD1 | No | No | 51174 | Q9UJT1 |
| TVIS30044538 | HIV | ENSG00000108423.16 | protein_coding | TUBD1 | No | No | 51174 | Q9UJT1 |
| TVIS20004431 | HPV | ENSG00000108423.16 | protein_coding | TUBD1 | No | No | 51174 | Q9UJT1 |
| TVIS20007824 | HPV | ENSG00000108423.16 | protein_coding | TUBD1 | No | No | 51174 | Q9UJT1 |
| TVIS20005056 | HPV | ENSG00000108423.16 | protein_coding | TUBD1 | No | No | 51174 | Q9UJT1 |
| TVIS20015904 | HPV | ENSG00000108423.16 | protein_coding | TUBD1 | No | No | 51174 | Q9UJT1 |
| TVIS20015848 | HPV | ENSG00000108423.16 | protein_coding | TUBD1 | No | No | 51174 | Q9UJT1 |
| TVIS20016610 | HPV | ENSG00000108423.16 | protein_coding | TUBD1 | No | No | 51174 | Q9UJT1 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | TUBD1 |
|---|---|
| DrugBank ID | DB00570 |
| Drug Name | Vinblastine |
| Target ID | BE0003711 |
| UniProt ID | Q9UJT1 |
| Regulation Type | binder |
| PubMed IDs | 18220533; 1818332; 9664292; 15579115; 14619954 |
| Citations | Jordan MA, Kamath K: How do microtubule-targeted drugs work? An overview. Curr Cancer Drug Targets. 2007 Dec;7(8):730-42.@@Correia JJ: Effects of antimitotic agents on tubulin-nucleotide interactions. Pharmacol Ther. 1991 Nov;52(2):127-47.@@Jordan A, Hadfield JA, Lawrence NJ, McGown AT: Tubulin as a target for anticancer drugs: agents which interact with the mitotic spindle. Med Res Rev. 1998 Jul;18(4):259-96.@@Islam MN, Iskander MN: Microtubulin binding sites as target for developing anticancer agents. Mini Rev Med Chem. 2004 Dec;4(10):1077-104.@@Gupta S, Bhattacharyya B: Antimicrotubular drugs binding to vinca domain of tubulin. Mol Cell Biochem. 2003 Nov;253(1-2):41-7. |
| Groups | Approved |
| Direct Classification | Vinca alkaloids |
| SMILES | [H][C@@]12N(C)C3=CC(OC)=C(C=C3[C@@]11CCN3CC=C[C@@](CC)([C@@H](OC(C)=O)[C@]2(O)C(=O)OC)[C@@]13[H])[C@]1(C[C@@]2([H])CN(C[C@](O)(CC)C2)CCC2=C1NC1=C2C=CC=C1)C(=O)OC |
| Pathways | Vinblastine Action Pathway |
| PharmGKB | PA451877 |
| ChEMBL | CHEMBL159 |
