| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30086172 | HIV | ENSG00000186716.21 | protein_coding | BCR | Yes | No | 613 | P11274 |
| TVIS30084988 | HIV | ENSG00000186716.21 | protein_coding | BCR | Yes | No | 613 | P11274 |
| TVIS30055183 | HIV | ENSG00000186716.21 | protein_coding | BCR | Yes | No | 613 | P11274 |
| TVIS30055184 | HIV | ENSG00000186716.21 | protein_coding | BCR | Yes | No | 613 | P11274 |
| TVIS30055185 | HIV | ENSG00000186716.21 | protein_coding | BCR | Yes | No | 613 | P11274 |
| TVIS30055186 | HIV | ENSG00000186716.21 | protein_coding | BCR | Yes | No | 613 | P11274 |
| TVIS30055187 | HIV | ENSG00000186716.21 | protein_coding | BCR | Yes | No | 613 | P11274 |
| TVIS20038778 | HPV | ENSG00000186716.21 | protein_coding | BCR | Yes | No | 613 | P11274 |
| TVIS20023449 | HPV | ENSG00000186716.21 | protein_coding | BCR | Yes | No | 613 | P11274 |
| TVIS44030081 | HTLV-1 | ENSG00000186716.21 | protein_coding | BCR | Yes | No | 613 | P11274 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | BCR |
|---|---|
| DrugBank ID | DB00619 |
| Drug Name | Imatinib |
| Target ID | BE0004743 |
| UniProt ID | P11274 |
| Regulation Type | inhibitor |
| PubMed IDs | 15206509; 20072827; 12600228; 23226582 |
| Citations | Nadal E, Olavarria E: Imatinib mesylate (Gleevec/Glivec) a molecular-targeted therapy for chronic myeloid leukaemia and other malignancies. Int J Clin Pract. 2004 May;58(5):511-6.@@Waller CF: Imatinib mesylate. Recent Results Cancer Res. 2010;184:3-20. doi: 10.1007/978-3-642-01222-8_1.@@Croom KF, Perry CM: Imatinib mesylate: in the treatment of gastrointestinal stromal tumours. Drugs. 2003;63(5):513-22; discussion 523-4.@@Reddy EP, Aggarwal AK: The ins and outs of bcr-abl inhibition. Genes Cancer. 2012 May;3(5-6):447-54. doi: 10.1177/1947601912462126. |
| Groups | Approved |
| Direct Classification | Benzanilides |
| SMILES | CN1CCN(CC2=CC=C(C=C2)C(=O)NC2=CC(NC3=NC=CC(=N3)C3=CN=CC=C3)=C(C)C=C2)CC1 |
| Pathways | Imatinib Inhibition of BCR-ABL |
| PharmGKB | PA10804 |
| ChEMBL | CHEMBL941 |
