| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30002214 | HIV | ENSG00000125384.8 | protein_coding | PTGER2 | No | No | 5732 | P43116 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PTGER2 |
|---|---|
| DrugBank ID | DB00374 |
| Drug Name | Treprostinil |
| Target ID | BE0000368 |
| UniProt ID | P43116 |
| Regulation Type | agonist |
| PubMed IDs | 31403254; 28399721 |
| Citations | Lindegaard Pedersen M, Kruger M, Grimm D, Infanger M, Wehland M: The prostacyclin analogue treprostinil in the treatment of pulmonary arterial hypertension. Basic Clin Pharmacol Toxicol. 2019 Aug 12. doi: 10.1111/bcpt.13305.@@Del Pozo R, Hernandez Gonzalez I, Escribano-Subias P: The prostacyclin pathway in pulmonary arterial hypertension: a clinical review. Expert Rev Respir Med. 2017 Jun;11(6):491-503. doi: 10.1080/17476348.2017.1317599. Epub 2017 Apr 24. |
| Groups | Approved; Investigational |
| Direct Classification | Phenoxyacetic acid derivatives |
| SMILES | [H][C@]12C[C@@H](O)[C@H](CC[C@@H](O)CCCCC)[C@@]1([H])CC1=C(C2)C(OCC(O)=O)=CC=C1 |
| Pathways | |
| PharmGKB | PA164768801 |
| ChEMBL | CHEMBL1237119 |
