| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30002214 | HIV | ENSG00000125384.8 | protein_coding | PTGER2 | No | No | 5732 | P43116 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | PTGER2 |
|---|---|
| DrugBank ID | DB00770 |
| Drug Name | Alprostadil |
| Target ID | BE0000368 |
| UniProt ID | P43116 |
| Regulation Type | agonist |
| PubMed IDs | 10509658; 15840408; 9313928 |
| Citations | Dijkstra BG, Schneemann A, Hoyng PF: Flow after prostaglandin E1 is mediated by receptor-coupled adenylyl cyclase in human anterior segments. Invest Ophthalmol Vis Sci. 1999 Oct;40(11):2622-6.@@Takahashi HK, Iwagaki H, Tamura R, Katsuno G, Xue D, Sugita S, Mori S, Yoshino T, Tanaka N, Nishibori M: Differential effect of prostaglandins E1 and E2 on lipopolysaccharide-induced adhesion molecule expression on human monocytes. Eur J Pharmacol. 2005 Apr 11;512(2-3):223-30.@@Kiriyama M, Ushikubi F, Kobayashi T, Hirata M, Sugimoto Y, Narumiya S: Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells. Br J Pharmacol. 1997 Sep;122(2):217-24. |
| Groups | Approved; Investigational |
| Direct Classification | |
| SMILES | CCCCC[C@H](O)C=C[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O |
| Pathways | |
| PharmGKB | PA448334 |
| ChEMBL | CHEMBL495 |
