| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10049176 | HBV | ENSG00000198074.10 | protein_coding | AKR1B10 | No | No | 57016 | O60218 |
| TVIS10049177 | HBV | ENSG00000198074.10 | protein_coding | AKR1B10 | No | No | 57016 | O60218 |
| TVIS44016725 | HTLV-1 | ENSG00000198074.10 | protein_coding | AKR1B10 | No | No | 57016 | O60218 |
| TVIS44049062 | HTLV-1 | ENSG00000198074.10 | protein_coding | AKR1B10 | No | No | 57016 | O60218 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | AKR1B10 |
|---|---|
| DrugBank ID | DB02021 |
| Drug Name | Fidarestat |
| Target ID | BE0004353 |
| UniProt ID | O60218 |
| Regulation Type | inhibitor |
| PubMed IDs | 23295227 |
| Citations | Ruiz FX, Cousido-Siah A, Mitschler A, Farres J, Pares X, Podjarny A: X-ray structure of the V301L aldo-keto reductase 1B10 complexed with NADP(+) and the potent aldose reductase inhibitor fidarestat: implications for inhibitor binding and selectivity. Chem Biol Interact. 2013 Feb 25;202(1-3):178-85. doi: 10.1016/j.cbi.2012.12.013. Epub 2013 Jan 4. |
| Groups | Experimental |
| Direct Classification | Hydantoins |
| SMILES | NC(=O)[C@@H]1C[C@]2(NC(=O)NC2=O)C2=C(O1)C=CC(F)=C2 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL84446 |
