| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10049176 | HBV | ENSG00000198074.10 | protein_coding | AKR1B10 | No | No | 57016 | O60218 |
| TVIS10049177 | HBV | ENSG00000198074.10 | protein_coding | AKR1B10 | No | No | 57016 | O60218 |
| TVIS44016725 | HTLV-1 | ENSG00000198074.10 | protein_coding | AKR1B10 | No | No | 57016 | O60218 |
| TVIS44049062 | HTLV-1 | ENSG00000198074.10 | protein_coding | AKR1B10 | No | No | 57016 | O60218 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | AKR1B10 |
|---|---|
| DrugBank ID | DB00605 |
| Drug Name | Sulindac |
| Target ID | BE0004353 |
| UniProt ID | O60218 |
| Regulation Type | inhibitor |
| PubMed IDs | 25532697 |
| Citations | Cousido-Siah A, Ruiz FX, Crespo I, Porte S, Mitschler A, Pares X, Podjarny A, Farres J: Structural analysis of sulindac as an inhibitor of aldose reductase and AKR1B10. Chem Biol Interact. 2015 Jun 5;234:290-6. doi: 10.1016/j.cbi.2014.12.018. Epub 2014 Dec 20. |
| Groups | Approved; Investigational |
| Direct Classification | Indenes and isoindenes |
| SMILES | CC1=C(CC(O)=O)C2=CC(F)=CC=C2C1=C/C1=CC=C(C=C1)S(C)=O |
| Pathways | Sulindac Action Pathway |
| PharmGKB | PA451565 |
| ChEMBL | CHEMBL15770 |
