Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS30020123HIVENSG00000111275.13protein_codingALDH2NoYes217P05091
TVIS20050733HPVENSG00000111275.13protein_codingALDH2NoYes217P05091
TVIS44023345HTLV-1ENSG00000111275.13protein_codingALDH2NoYes217P05091
TCGA Plot Options
Drug Information
GeneALDH2
DrugBank IDDB00536
Drug NameGuanidine
Target IDBE0000133
UniProt IDP05091
Regulation Typeinhibitor
PubMed IDs9271349; 6100768
CitationsKikonyogo A, Pietruszko R: Cimetidine and other H2-receptor antagonists as inhibitors of human E3 aldehyde dehydrogenase. Mol Pharmacol. 1997 Aug;52(2):267-71. doi: 10.1124/mol.52.2.267.@@Kopczynski Z, Dryl T, Chmiel J: Studies on the effects of low-molecular uraemic toxins on the activity of 3-phospho-D-glycerol aldehyde dehydrogenase (E.C.1.2.1.12) in human erythrocytes. Acta Physiol Pol. 1984 Sep-Dec;35(5-6):539-45.
GroupsApproved
Direct ClassificationGuanidines
SMILESNC(N)=N
Pathways
PharmGKBPA164781028
ChEMBLCHEMBL821