| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30020123 | HIV | ENSG00000111275.13 | protein_coding | ALDH2 | No | Yes | 217 | P05091 |
| TVIS20050733 | HPV | ENSG00000111275.13 | protein_coding | ALDH2 | No | Yes | 217 | P05091 |
| TVIS44023345 | HTLV-1 | ENSG00000111275.13 | protein_coding | ALDH2 | No | Yes | 217 | P05091 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ALDH2 |
|---|---|
| DrugBank ID | DB00822 |
| Drug Name | Disulfiram |
| Target ID | BE0000133 |
| UniProt ID | P05091 |
| Regulation Type | inhibitor |
| PubMed IDs | 16051882; 17220694 |
| Citations | Mackenzie IS, Maki-Petaja KM, McEniery CM, Bao YP, Wallace SM, Cheriyan J, Monteith S, Brown MJ, Wilkinson IB: Aldehyde dehydrogenase 2 plays a role in the bioactivation of nitroglycerin in humans. Arterioscler Thromb Vasc Biol. 2005 Sep;25(9):1891-5. Epub 2005 Jul 28.@@Ho MP, Yo CH, Liu CM, Chen CL, Lee CC: Refractive hypotension in a patient with disulfiram-ethanol reaction. Am J Med Sci. 2007 Jan;333(1):53-5. |
| Groups | Approved |
| Direct Classification | Thiuram disulfides |
| SMILES | CCN(CC)C(=S)SSC(=S)N(CC)CC |
| Pathways | Disulfiram Action Pathway |
| PharmGKB | PA449376 |
| ChEMBL | CHEMBL964 |
