| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30070814 | HIV | ENSG00000165272.16 | protein_coding | AQP3 | No | No | 360 | Q92482 |
| TVIS44032421 | HTLV-1 | ENSG00000165272.16 | protein_coding | AQP3 | No | No | 360 | Q92482 |
| TVIS44017074 | HTLV-1 | ENSG00000165272.16 | protein_coding | AQP3 | No | No | 360 | Q92482 |
| TVIS44001054 | HTLV-1 | ENSG00000165272.16 | protein_coding | AQP3 | No | No | 360 | Q92482 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | AQP3 |
|---|---|
| DrugBank ID | DB11365 |
| Drug Name | Sennosides |
| Target ID | BE0009664 |
| UniProt ID | Q92482 |
| Regulation Type | inhibitor |
| PubMed IDs | 24412547 |
| Citations | Kon R, Ikarashi N, Nagoya C, Takayama T, Kusunoki Y, Ishii M, Ueda H, Ochiai W, Machida Y, Sugita K, Sugiyama K: Rheinanthrone, a metabolite of sennoside A, triggers macrophage activation to decrease aquaporin-3 expression in the colon, causing the laxative effect of rhubarb extract. J Ethnopharmacol. 2014 Feb 27;152(1):190-200. doi: 10.1016/j.jep.2013.12.055. Epub 2014 Jan 8. |
| Groups | Experimental |
| Direct Classification | |
| SMILES | OCC1OC(OC2=C3C(=O)C4=C(C=C(C=C4O)C(O)=O)C(C4C5=CC=CC(OC6OC(CO)C(O)C(O)C6O)=C5C(=O)C5=C4C=C(C=C5O)C(O)=O)C3=CC=C2)C(O)C(O)C1O |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL54481 |
