| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10025415 | HBV | ENSG00000257335.8 | protein_coding | MGAM | Yes | No | 8972 | E7ER45 O43451 |
| TVIS30080980 | HIV | ENSG00000257335.8 | protein_coding | MGAM | Yes | No | 8972 | E7ER45 O43451 |
| TVIS20062222 | HPV | ENSG00000257335.8 | protein_coding | MGAM | Yes | No | 8972 | E7ER45 O43451 |
| TVIS20031824 | HPV | ENSG00000257335.8 | protein_coding | MGAM | Yes | No | 8972 | E7ER45 O43451 |
| TVIS44022679 | HTLV-1 | ENSG00000257335.8 | protein_coding | MGAM | Yes | No | 8972 | E7ER45 O43451 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | MGAM |
|---|---|
| DrugBank ID | DB00491 |
| Drug Name | Miglitol |
| Target ID | BE0000837 |
| UniProt ID | O43451 |
| Regulation Type | antagonist |
| PubMed IDs | 9951949; 16817895; 19818342; 11752352 |
| Citations | Mooradian AD, Thurman JE: Drug therapy of postprandial hyperglycaemia. Drugs. 1999 Jan;57(1):19-29.@@Rossi EJ, Sim L, Kuntz DA, Hahn D, Johnston BD, Ghavami A, Szczepina MG, Kumar NS, Sterchi EE, Nichols BL, Pinto BM, Rose DR: Inhibition of recombinant human maltase glucoamylase by salacinol and derivatives. FEBS J. 2006 Jun;273(12):2673-83.@@Fukaya N, Mochizuki K, Tanaka Y, Kumazawa T, Jiuxin Z, Fuchigami M, Goda T: The alpha-glucosidase inhibitor miglitol delays the development of diabetes and dysfunctional insulin secretion in pancreatic beta-cells in OLETF rats. Eur J Pharmacol. 2009 Dec 10;624(1-3):51-7. doi: 10.1016/j.ejphar.2009.09.048. Epub 2009 Oct 7.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. |
| Groups | Approved |
| Direct Classification | Piperidines |
| SMILES | OCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO |
| Pathways | |
| PharmGKB | PA164776726 |
| ChEMBL | CHEMBL1561 |
