| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10025415 | HBV | ENSG00000257335.8 | protein_coding | MGAM | Yes | No | 8972 | E7ER45 O43451 |
| TVIS30080980 | HIV | ENSG00000257335.8 | protein_coding | MGAM | Yes | No | 8972 | E7ER45 O43451 |
| TVIS20062222 | HPV | ENSG00000257335.8 | protein_coding | MGAM | Yes | No | 8972 | E7ER45 O43451 |
| TVIS20031824 | HPV | ENSG00000257335.8 | protein_coding | MGAM | Yes | No | 8972 | E7ER45 O43451 |
| TVIS44022679 | HTLV-1 | ENSG00000257335.8 | protein_coding | MGAM | Yes | No | 8972 | E7ER45 O43451 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | MGAM |
|---|---|
| DrugBank ID | DB00284 |
| Drug Name | Acarbose |
| Target ID | BE0000837 |
| UniProt ID | O43451 |
| Regulation Type | inhibitor |
| PubMed IDs | 16702880; 19275550; 8893066 |
| Citations | Zhang H, Kallwass H, Young SP, Carr C, Dai J, Kishnani PS, Millington DS, Keutzer J, Chen YT, Bali D: Comparison of maltose and acarbose as inhibitors of maltase-glucoamylase activity in assaying acid alpha-glucosidase activity in dried blood spots for the diagnosis of infantile Pompe disease. Genet Med. 2006 May;8(5):302-6.@@Yamagishi S, Matsui T, Ueda S, Fukami K, Okuda S: Clinical utility of acarbose, an alpha-glucosidase inhibitor in cardiometabolic disorders. Curr Drug Metab. 2009 Feb;10(2):159-63.@@Martin AE, Montgomery PA: Acarbose: an alpha-glucosidase inhibitor. Am J Health Syst Pharm. 1996 Oct 1;53(19):2277-90; quiz 2336-7. doi: 10.1093/ajhp/53.19.2277. |
| Groups | Approved; Investigational |
| Direct Classification | Aminocyclitol glycosides |
| SMILES | [H]C(=O)[C@H](O)[C@@H](O)[C@]([H])(O[C@@]1([H])O[C@H](CO)[C@@]([H])(O[C@H]2O[C@H](C)[C@@H](N[C@@]3([H])C=C(CO)[C@@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O)[C@H](O)CO |
| Pathways | |
| PharmGKB | PA448010 |
| ChEMBL | CHEMBL1566 |
