| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10040202 | HBV | ENSG00000157404.17 | protein_coding | KIT | Yes | No | 3815 | P10721 |
| TVIS10040086 | HBV | ENSG00000157404.17 | protein_coding | KIT | Yes | No | 3815 | P10721 |
| TVIS30010849 | HIV | ENSG00000157404.17 | protein_coding | KIT | Yes | No | 3815 | P10721 |
| TVIS20037373 | HPV | ENSG00000157404.17 | protein_coding | KIT | Yes | No | 3815 | P10721 |
| TVIS20039601 | HPV | ENSG00000157404.17 | protein_coding | KIT | Yes | No | 3815 | P10721 |
| TVIS44012431 | HTLV-1 | ENSG00000157404.17 | protein_coding | KIT | Yes | No | 3815 | P10721 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | KIT |
|---|---|
| DrugBank ID | DB15233 |
| Drug Name | Avapritinib |
| Target ID | BE0000453 |
| UniProt ID | P10721 |
| Regulation Type | inhibitor |
| PubMed IDs | 31117741 |
| Citations | Wu CP, Lusvarghi S, Wang JC, Hsiao SH, Huang YH, Hung TH, Ambudkar SV: Avapritinib: A Selective Inhibitor of KIT and PDGFRalpha that Reverses ABCB1 and ABCG2-Mediated Multidrug Resistance in Cancer Cell Lines. Mol Pharm. 2019 Jul 1;16(7):3040-3052. doi: 10.1021/acs.molpharmaceut.9b00274. Epub 2019 Jun 4. |
| Groups | Approved; Investigational |
| Direct Classification | |
| SMILES | CN1C=C(C=N1)C1=CN2N=CN=C(N3CCN(CC3)C3=NC=C(C=N3)[C@@](C)(N)C3=CC=C(F)C=C3)C2=C1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL4204794 |
