| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30081548 | HIV | ENSG00000176884.17 | protein_coding | GRIN1 | No | No | 2902 | Q05586 Q5VSF9 |
| TVIS30072672 | HIV | ENSG00000176884.17 | protein_coding | GRIN1 | No | No | 2902 | Q05586 Q5VSF9 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | GRIN1 |
|---|---|
| DrugBank ID | DB01043 |
| Drug Name | Memantine |
| Target ID | BE0000365 |
| UniProt ID | Q05586 |
| Regulation Type | binder |
| PubMed IDs | 19687120 |
| Citations | Kotermanski SE, Wood JT, Johnson JW: Memantine binding to a superficial site on NMDA receptors contributes to partial trapping. J Physiol. 2009 Oct 1;587(Pt 19):4589-604. doi: 10.1113/jphysiol.2009.176297. Epub 2009 Aug 17. |
| Groups | Approved; Investigational |
| Direct Classification | Monoalkylamines |
| SMILES | CC12CC3CC(C)(C1)CC(N)(C3)C2 |
| Pathways | |
| PharmGKB | PA10364 |
| ChEMBL | CHEMBL807 |