| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30081548 | HIV | ENSG00000176884.17 | protein_coding | GRIN1 | No | No | 2902 | Q05586 Q5VSF9 |
| TVIS30072672 | HIV | ENSG00000176884.17 | protein_coding | GRIN1 | No | No | 2902 | Q05586 Q5VSF9 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | GRIN1 |
|---|---|
| DrugBank ID | DB04620 |
| Drug Name | Cycloleucine |
| Target ID | BE0000365 |
| UniProt ID | Q05586 |
| Regulation Type | |
| PubMed IDs | 2170997; 2556198; 2843389; 10592235 |
| Citations | Herberg LJ, Rose IC: Effects of D-cycloserine and cycloleucine, ligands for the NMDA-associated strychnine-insensitive glycine site, on brain-stimulation reward and spontaneous locomotion. Pharmacol Biochem Behav. 1990 Aug;36(4):735-8.@@Hershkowitz N, Rogawski MA: Cycloleucine blocks NMDA responses in cultured hippocampal neurones under voltage clamp: antagonism at the strychnine-insensitive glycine receptor. Br J Pharmacol. 1989 Nov;98(3):1005-13.@@Snell LD, Johnson KM: Cycloleucine competitively antagonizes the strychnine-insensitive glycine receptor. Eur J Pharmacol. 1988 Jun 22;151(1):165-6.@@Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. |
| Groups | Experimental |
| Direct Classification | L-alpha-amino acids |
| SMILES | NC1(CCCC1)C(O)=O |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL295830 |
