| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10015691 | HBV | ENSG00000134460.19 | protein_coding | IL2RA | No | No | 3559 | P01589 Q5W005 |
| TVIS10026184 | HBV | ENSG00000134460.19 | protein_coding | IL2RA | No | No | 3559 | P01589 Q5W005 |
| TVIS30011403 | HIV | ENSG00000134460.19 | protein_coding | IL2RA | No | No | 3559 | P01589 Q5W005 |
| TVIS30004372 | HIV | ENSG00000134460.19 | protein_coding | IL2RA | No | No | 3559 | P01589 Q5W005 |
| TVIS30010128 | HIV | ENSG00000134460.19 | protein_coding | IL2RA | No | No | 3559 | P01589 Q5W005 |
| TVIS20032371 | HPV | ENSG00000134460.19 | protein_coding | IL2RA | No | No | 3559 | P01589 Q5W005 |
| TVIS20040966 | HPV | ENSG00000134460.19 | protein_coding | IL2RA | No | No | 3559 | P01589 Q5W005 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | IL2RA |
|---|---|
| DrugBank ID | DB00074 |
| Drug Name | Basiliximab |
| Target ID | BE0000658 |
| UniProt ID | P01589 |
| Regulation Type | antibody |
| PubMed IDs | 12591363; 9695721; 16908318; 10512062; 10567956; 11752352 |
| Citations | Choy BY, Chan TM, Li FK, Lui SL, Lo WK, Yip T, Tse KC, Lai KN: IL2-receptor antagonist (basiliximab) induction therapy is associated with lower morbidity and mortality in renal transplant recipients. Transplant Proc. 2003 Feb;35(1):195.@@Kovarik J, Breidenbach T, Gerbeau C, Korn A, Schmidt AG, Nashan B: Disposition and immunodynamics of basiliximab in liver allograft recipients. Clin Pharmacol Ther. 1998 Jul;64(1):66-72.@@Garcia CD, Bittencourt VB, Tumelero A, Antonello JS, Malheiros D, Garcia VD: Plasmapheresis for recurrent posttransplant focal segmental glomerulosclerosis. Transplant Proc. 2006 Jul-Aug;38(6):1904-5.@@Berard JL, Velez RL, Freeman RB, Tsunoda SM: A review of interleukin-2 receptor antagonists in solid organ transplantation. Pharmacotherapy. 1999 Oct;19(10):1127-37.@@Mentre F, Kovarik J, Gerbeau C: Constructing a prediction interval for time to reach a threshold concentration based on a population pharmacokinetic analysis: an application to basiliximab in renal transplantation. J Pharmacokinet Biopharm. 1999 Apr;27(2):213-30.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. |
| Groups | Approved; Investigational |
| Direct Classification | Peptides |
| SMILES | |
| Pathways | |
| PharmGKB | PA164747126 |
| ChEMBL | CHEMBL1201439 |
