| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10015691 | HBV | ENSG00000134460.19 | protein_coding | IL2RA | No | No | 3559 | P01589 Q5W005 |
| TVIS10026184 | HBV | ENSG00000134460.19 | protein_coding | IL2RA | No | No | 3559 | P01589 Q5W005 |
| TVIS30011403 | HIV | ENSG00000134460.19 | protein_coding | IL2RA | No | No | 3559 | P01589 Q5W005 |
| TVIS30004372 | HIV | ENSG00000134460.19 | protein_coding | IL2RA | No | No | 3559 | P01589 Q5W005 |
| TVIS30010128 | HIV | ENSG00000134460.19 | protein_coding | IL2RA | No | No | 3559 | P01589 Q5W005 |
| TVIS20032371 | HPV | ENSG00000134460.19 | protein_coding | IL2RA | No | No | 3559 | P01589 Q5W005 |
| TVIS20040966 | HPV | ENSG00000134460.19 | protein_coding | IL2RA | No | No | 3559 | P01589 Q5W005 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | IL2RA |
|---|---|
| DrugBank ID | DB16411 |
| Drug Name | Camidanlumab tesirine |
| Target ID | BE0000658 |
| UniProt ID | P01589 |
| Regulation Type | antibody |
| PubMed IDs | 32521310; 32912922 |
| Citations | Goldberg AD, Atallah E, Rizzieri D, Walter RB, Chung KY, Spira A, Stock W, Tallman MS, Cruz HG, Boni J, Havenith KEG, Chao G, Feingold JM, Wuerthner J, Solh M: Camidanlumab tesirine, an antibody-drug conjugate, in relapsed/refractory CD25-positive acute myeloid leukemia or acute lymphoblastic leukemia: A phase I study. Leuk Res. 2020 Aug;95:106385. doi: 10.1016/j.leukres.2020.106385. Epub 2020 Jun 7.@@Zammarchi F, Havenith K, Bertelli F, Vijayakrishnan B, Chivers S, van Berkel PH: CD25-targeted antibody-drug conjugate depletes regulatory T cells and eliminates established syngeneic tumors via antitumor immunity. J Immunother Cancer. 2020 Sep;8(2). pii: jitc-2020-000860. doi: 10.1136/jitc-2020-000860. |
| Groups | Investigational |
| Direct Classification | Peptides |
| SMILES | |
| Pathways | |
| PharmGKB | |
| ChEMBL |
