| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30020145 | HIV | ENSG00000120659.16 | protein_coding | TNFSF11 | No | No | 8600 | O14788 Q5T9Y4 |
| TVIS20039495 | HPV | ENSG00000120659.16 | protein_coding | TNFSF11 | No | No | 8600 | O14788 Q5T9Y4 |
| TVIS44000612 | HTLV-1 | ENSG00000120659.16 | protein_coding | TNFSF11 | No | No | 8600 | O14788 Q5T9Y4 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | TNFSF11 |
|---|---|
| DrugBank ID | DB06643 |
| Drug Name | Denosumab |
| Target ID | BE0003517 |
| UniProt ID | O14788 |
| Regulation Type | antibody |
| PubMed IDs | 18685421; 16702197 |
| Citations | Lipton A, Jun S: RANKL inhibition in the treatment of bone metastases. Curr Opin Support Palliat Care. 2008 Sep;2(3):197-203. doi: 10.1097/SPC.0b013e32830baac2.@@Westenfeld R, Ketteler M, Brandenburg VM: Anti-RANKL therapy--implications for the bone-vascular-axis in CKD? Denosumab in post-menopausal women with low bone mineral density. Nephrol Dial Transplant. 2006 Aug;21(8):2075-7. Epub 2006 May 15. |
| Groups | Approved |
| Direct Classification | Peptides |
| SMILES | |
| Pathways | |
| PharmGKB | PA166048634 |
| ChEMBL | CHEMBL1237023 |
