| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30020145 | HIV | ENSG00000120659.16 | protein_coding | TNFSF11 | No | No | 8600 | O14788 Q5T9Y4 |
| TVIS20039495 | HPV | ENSG00000120659.16 | protein_coding | TNFSF11 | No | No | 8600 | O14788 Q5T9Y4 |
| TVIS44000612 | HTLV-1 | ENSG00000120659.16 | protein_coding | TNFSF11 | No | No | 8600 | O14788 Q5T9Y4 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | TNFSF11 |
|---|---|
| DrugBank ID | DB11582 |
| Drug Name | Thiocolchicoside |
| Target ID | BE0003517 |
| UniProt ID | O14788 |
| Regulation Type | antagonist |
| PubMed IDs | 21955206 |
| Citations | Reuter S, Gupta SC, Phromnoi K, Aggarwal BB: Thiocolchicoside suppresses osteoclastogenesis induced by RANKL and cancer cells through inhibition of inflammatory pathways: a new use for an old drug. Br J Pharmacol. 2012 Apr;165(7):2127-39. doi: 10.1111/j.1476-5381.2011.01702.x. |
| Groups | Experimental |
| Direct Classification | Phenolic glycosides |
| SMILES | COC1=C(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)C=C2CC[C@H](NC(C)=O)C3=CC(=O)C(SC)=CC=C3C2=C1OC |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL213907 |
