| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30002701 | HIV | ENSG00000126351.13 | protein_coding | THRA | No | No | 7067 | P10827 Q6FH41 |
| TVIS30086145 | HIV | ENSG00000126351.13 | protein_coding | THRA | No | No | 7067 | P10827 Q6FH41 |
| TVIS30043746 | HIV | ENSG00000126351.13 | protein_coding | THRA | No | No | 7067 | P10827 Q6FH41 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | THRA |
|---|---|
| DrugBank ID | DB01118 |
| Drug Name | Amiodarone |
| Target ID | BE0009811 |
| UniProt ID | P10828 |
| Regulation Type | antagonist |
| PubMed IDs | 11806713; 2910914; 23148177 |
| Citations | Carlsson B, Singh BN, Temciuc M, Nilsson S, Li YL, Mellin C, Malm J: Synthesis and preliminary characterization of a novel antiarrhythmic compound (KB130015) with an improved toxicity profile compared with amiodarone. J Med Chem. 2002 Jan 31;45(3):623-30.@@Norman MF, Lavin TN: Antagonism of thyroid hormone action by amiodarone in rat pituitary tumor cells. J Clin Invest. 1989 Jan;83(1):306-13. doi: 10.1172/JCI113874.@@Narayana SK, Woods DR, Boos CJ: Management of amiodarone-related thyroid problems. Ther Adv Endocrinol Metab. 2011 Jun;2(3):115-26. doi: 10.1177/2042018811398516. |
| Groups | Approved; Investigational |
| Direct Classification | Aryl-phenylketones |
| SMILES | CCCCC1=C(C(=O)C2=CC(I)=C(OCCN(CC)CC)C(I)=C2)C2=C(O1)C=CC=C2 |
| Pathways | Amiodarone Action Pathway |
| PharmGKB | PA448383 |
| ChEMBL | CHEMBL633 |
