| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30008124 | HIV | ENSG00000128271.22 | protein_coding | ADORA2A | No | No | 135 | P29274 X5DNB4 |
| TVIS44031350 | HTLV-1 | ENSG00000128271.22 | protein_coding | ADORA2A | No | No | 135 | P29274 X5DNB4 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ADORA2A |
|---|---|
| DrugBank ID | DB00806 |
| Drug Name | Pentoxifylline |
| Target ID | BE0000924 |
| UniProt ID | P29274 |
| Regulation Type | agonist |
| PubMed IDs | 19997047; 23699177 |
| Citations | Kreth S, Ledderose C, Luchting B, Weis F, Thiel M: Immunomodulatory properties of pentoxifylline are mediated via adenosine-dependent pathways. Shock. 2010 Jul;34(1):10-6. doi: 10.1097/SHK.0b013e3181cdc3e2.@@Konrad FM, Neudeck G, Vollmer I, Ngamsri KC, Thiel M, Reutershan J: Protective effects of pentoxifylline in pulmonary inflammation are adenosine receptor A2A dependent. FASEB J. 2013 Sep;27(9):3524-35. doi: 10.1096/fj.13-228122. Epub 2013 May 22. |
| Groups | Approved; Investigational |
| Direct Classification | Xanthines |
| SMILES | CN1C=NC2=C1C(=O)N(CCCCC(C)=O)C(=O)N2C |
| Pathways | |
| PharmGKB | PA450864 |
| ChEMBL | CHEMBL628 |
