| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10009794 | HBV | ENSG00000114200.10 | protein_coding | BCHE | No | No | 590 | P06276 |
| TVIS10036366 | HBV | ENSG00000114200.10 | protein_coding | BCHE | No | No | 590 | P06276 |
| TVIS30058841 | HIV | ENSG00000114200.10 | protein_coding | BCHE | No | No | 590 | P06276 |
| TVIS30058842 | HIV | ENSG00000114200.10 | protein_coding | BCHE | No | No | 590 | P06276 |
| TVIS30058843 | HIV | ENSG00000114200.10 | protein_coding | BCHE | No | No | 590 | P06276 |
| TVIS30058844 | HIV | ENSG00000114200.10 | protein_coding | BCHE | No | No | 590 | P06276 |
| TVIS30058845 | HIV | ENSG00000114200.10 | protein_coding | BCHE | No | No | 590 | P06276 |
| TVIS30058846 | HIV | ENSG00000114200.10 | protein_coding | BCHE | No | No | 590 | P06276 |
| TVIS30058847 | HIV | ENSG00000114200.10 | protein_coding | BCHE | No | No | 590 | P06276 |
| TVIS30058848 | HIV | ENSG00000114200.10 | protein_coding | BCHE | No | No | 590 | P06276 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | BCHE |
|---|---|
| DrugBank ID | DB00122 |
| Drug Name | Choline |
| Target ID | BE0002180 |
| UniProt ID | P06276 |
| Regulation Type | product of |
| PubMed IDs | 17329059; 16297435; 17636231; 17390078; 16376069 |
| Citations | Hsieh BC, Matsumoto K, Cheng TJ, Yuu G, Chen RL: Choline biosensor constructed with chitinous membrane from soldier crab and its application in measuring cholinesterase inhibitory activities. J Pharm Biomed Anal. 2007 Nov 30;45(4):673-8. Epub 2007 Jan 24.@@Amenta F, Tayebati SK, Vitali D, Di Tullio MA: Association with the cholinergic precursor choline alphoscerate and the cholinesterase inhibitor rivastigmine: an approach for enhancing cholinergic neurotransmission. Mech Ageing Dev. 2006 Feb;127(2):173-9. Epub 2005 Nov 16.@@Lurie S, Sadan O, Oron G, Fux A, Boaz M, Ezri T, Golan A, Bar J: Reduced pseudocholinesterase activity in patients with HELLP syndrome. Reprod Sci. 2007 Feb;14(2):192-6.@@Calaf GM, Roy D: Gene expression signature of parathion-transformed human breast epithelial cells. Int J Mol Med. 2007 May;19(5):741-50.@@Stoytcheva M, Zlatev R, Valdez B, Magnin JP, Velkova Z: Electrochemical sensor based on Arthrobacter globiformis for cholinesterase activity determination. Biosens Bioelectron. 2006 Jul 15;22(1):1-9. Epub 2005 Dec 20. |
| Groups | Approved; Nutraceutical |
| Direct Classification | Cholines |
| SMILES | C[N+](C)(C)CCO |
| Pathways | Phosphatidylcholine Biosynthesis PC(14:0/20:0); Phosphatidylcholine Biosynthesis PC(14:0/20:4(5Z,8Z,11Z,14Z)); Phosphatidylcholine Biosynthesis PC(15:0/20:3(8Z,11Z,14Z)); Phosphatidylcholine Biosynthesis PC(15:0/16:0); Phosphatidylcholine Biosynthesis PC(14:0/20:5(5Z,8Z,11Z,14Z,17Z)); Phosphatidylcholine Biosynthesis PC(14:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)); Phosphatidylcholine Biosynthesis PC(14:1(9Z)/16:0); Phosphatidylcholine Biosynthesis PC(14:0/20:2(11Z,14Z)); Phosphatidylcholine Biosynthesis PC(14:1(9Z)/16:1(9Z)); Phosphatidylcholine Biosynthesis PC(14:1(9Z)/22:2(13Z,16Z)); Phosphatidylcholine Biosynthesis PC(14:1(9Z)/24:0); Phosphatidylcholine Biosynthesis PC(14:0/15:0); Phosphatidylcholine Biosynthesis PC(15:0/14:0); Phosphatidylcholine Biosynthesis PC(15:0/20:4(5Z,8Z,11Z,14Z)); Phosphatidylcholine Biosynthesis PC(15:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)); Betaine Metabolism; Phosphatidylcholine Biosynthesis PC(14:0/20:1(11Z)); Phosphatidylcholine Biosynthesis PC(16:0/14:0); Phosphatidylcholine Biosynthesis PC(15:0/22:0); Phosphatidylcholine Biosynthesis PC(14:0/22:5(4Z,7Z,10Z,13Z,16Z)); Phosphatidylcholine Biosynthesis PC(15:0/16:1(9Z)); Phosphatidylcholine Biosynthesis PC(14:1(9Z)/14:0); Phosphatidylcholine Biosynthesis PC(15:0/20:1(11Z)); Phosphatidylcholine Biosynthesis PC(14:0/18:2(9Z,12Z)); Phosphatidylcholine Biosynthesis PC(14:0/14:0); Cystathionine beta-Synthase Deficiency; Phosphatidylcholine Biosynthesis PC(14:0/16:1(9Z)); Phosphatidylcholine Biosynthesis PC(15:0/18:0); Sarcosine Oncometabolite Pathway; Phosphatidylcholine Biosynthesis PC(14:1(9Z)/18:3(9Z,12Z,15Z)) |
| PharmGKB | PA448976 |
| ChEMBL | CHEMBL920 |