| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10039279 | HBV | ENSG00000140459.18 | protein_coding | CYP11A1 | No | No | 1583 | A0A0S2Z3R3 P05108 |
| TVIS20046919 | HPV | ENSG00000140459.18 | protein_coding | CYP11A1 | No | No | 1583 | A0A0S2Z3R3 P05108 |
| TVIS20014592 | HPV | ENSG00000140459.18 | protein_coding | CYP11A1 | No | No | 1583 | A0A0S2Z3R3 P05108 |
| TVIS44041870 | HTLV-1 | ENSG00000140459.18 | protein_coding | CYP11A1 | No | No | 1583 | A0A0S2Z3R3 P05108 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CYP11A1 |
|---|---|
| DrugBank ID | DB00357 |
| Drug Name | Aminoglutethimide |
| Target ID | BE0003537 |
| UniProt ID | P05108 |
| Regulation Type | inhibitor |
| PubMed IDs | 16817851; 11161433; 11752352 |
| Citations | Slominski A, Semak I, Wortsman J, Zjawiony J, Li W, Zbytek B, Tuckey RC: An alternative pathway of vitamin D metabolism. Cytochrome P450scc (CYP11A1)-mediated conversion to 20-hydroxyvitamin D2 and 17,20-dihydroxyvitamin D2. FEBS J. 2006 Jul;273(13):2891-901.@@Oka H, Emori Y, Hayashi Y, Nomoto K: Breakdown of Th cell immune responses and steroidogenic CYP11A1 expression in CD4+ T cells in a murine model implanted with B16 melanoma. Cell Immunol. 2000 Nov 25;206(1):7-15.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. |
| Groups | Approved; Investigational |
| Direct Classification | Aniline and substituted anilines |
| SMILES | CCC1(CCC(=O)NC1=O)C1=CC=C(N)C=C1 |
| Pathways | |
| PharmGKB | PA448375 |
| ChEMBL | CHEMBL488 |
