Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS44030856HTLV-1ENSG00000152661.9protein_codingGJA1NoNo2697P17302
TCGA Plot Options
Drug Information
GeneGJA1
DrugBank IDDB01136
Drug NameCarvedilol
Target IDBE0001095
UniProt IDP17302
Regulation Typeother
PubMed IDs16448880; 16563290
CitationsYeh HI, Lee PY, Su CH, Tian TY, Ko YS, Tsai CH: Reduced expression of endothelial connexins 43 and 37 in hypertensive rats is rectified after 7-day carvedilol treatment. Am J Hypertens. 2006 Feb;19(2):129-35.@@Fan SY, Ke YN, Zeng YJ, Wang Y, Cheng WL, Yang JR: [Effects and the mechanism of carvedilol on gap junctional intercellular communication in rat myocardium]. Zhonghua Xin Xue Guan Bing Za Zhi. 2005 Dec;33(12):1141-5.
GroupsApproved; Investigational
Direct ClassificationCarbazoles
SMILESCOC1=CC=CC=C1OCCNCC(O)COC1=CC=CC2=C1C1=CC=CC=C1N2
PathwaysCarvedilol Action Pathway
PharmGKBPA448817
ChEMBLCHEMBL723