| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10060391 | HBV | ENSG00000084110.11 | protein_coding | HAL | No | No | 3034 | P42357 |
| TVIS44005306 | HTLV-1 | ENSG00000084110.11 | protein_coding | HAL | No | No | 3034 | P42357 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | HAL |
|---|---|
| DrugBank ID | DB00117 |
| Drug Name | Histidine |
| Target ID | BE0000086 |
| UniProt ID | P42357 |
| Regulation Type | |
| PubMed IDs | 17191848; 17536021; 17185227; 17193285 |
| Citations | Viergutz S, Retey J: Kinetic analysis of the reactions catalyzed by histidine and phenylalanine ammonia lyases. Chem Biodivers. 2004 Feb;1(2):296-302.@@Lambrecht NW, Yakubov I, Sachs G: Fasting-induced changes in ECL cell gene expression. Physiol Genomics. 2007 Oct 22;31(2):183-92. Epub 2007 May 29.@@Watts KT, Mijts BN, Lee PC, Manning AJ, Schmidt-Dannert C: Discovery of a substrate selectivity switch in tyrosine ammonia-lyase, a member of the aromatic amino acid lyase family. Chem Biol. 2006 Dec;13(12):1317-26.@@Katona A, Tosa MI, Paizs C, Retey J: Inhibition of histidine ammonia lyase by heteroaryl-alanines and acrylates. Chem Biodivers. 2006 May;3(5):502-8. |
| Groups | Investigational; Nutraceutical |
| Direct Classification | Histidine and derivatives |
| SMILES | N[C@@H](CC1=CNC=N1)C(O)=O |
| Pathways | Clomocycline Action Pathway; Histidinemia; Rolitetracycline Action Pathway; Demeclocycline Action Pathway; Josamycin Action Pathway; Kanamycin Action Pathway; Gentamicin Action Pathway; Tobramycin Action Pathway; Carnosinuria, Carnosinemia; Azithromycin Action Pathway; Methylhistidine Metabolism; Clarithromycin Action Pathway; Minocycline Action Pathway; Troleandomycin Action Pathway; Amikacin Action Pathway; Streptomycin Action Pathway; Oxytetracycline Action Pathway; Tetracycline Action Pathway; Spectinomycin Action Pathway; Erythromycin Action Pathway; Netilmicin Action Pathway; beta-Alanine Metabolism; Doxycycline Action Pathway; Ammonia Recycling; Histidine Metabolism; Telithromycin Action Pathway; Neomycin Action Pathway; Roxithromycin Action Pathway; Arbekacin Action Pathway; Clindamycin Action Pathway |
| PharmGKB | PA449882 |
| ChEMBL | CHEMBL17962 |
