| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30006464 | HIV | ENSG00000100644.17 | protein_coding | HIF1A | Yes | No | 3091 | D0VY79 Q16665 |
| TVIS30015075 | HIV | ENSG00000100644.17 | protein_coding | HIF1A | Yes | No | 3091 | D0VY79 Q16665 |
| TVIS30000135 | HIV | ENSG00000100644.17 | protein_coding | HIF1A | Yes | No | 3091 | D0VY79 Q16665 |
| TVIS30036570 | HIV | ENSG00000100644.17 | protein_coding | HIF1A | Yes | No | 3091 | D0VY79 Q16665 |
| TVIS30036571 | HIV | ENSG00000100644.17 | protein_coding | HIF1A | Yes | No | 3091 | D0VY79 Q16665 |
| TVIS30036572 | HIV | ENSG00000100644.17 | protein_coding | HIF1A | Yes | No | 3091 | D0VY79 Q16665 |
| TVIS30017484 | HIV | ENSG00000100644.17 | protein_coding | HIF1A | Yes | No | 3091 | D0VY79 Q16665 |
| TVIS20020574 | HPV | ENSG00000100644.17 | protein_coding | HIF1A | Yes | No | 3091 | D0VY79 Q16665 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | HIF1A |
|---|---|
| DrugBank ID | DB01136 |
| Drug Name | Carvedilol |
| Target ID | BE0002374 |
| UniProt ID | Q16665 |
| Regulation Type | modulator |
| PubMed IDs | 15732037 |
| Citations | Shyu KG, Lu MJ, Chang H, Sun HY, Wang BW, Kuan P: Carvedilol modulates the expression of hypoxia-inducible factor-1alpha and vascular endothelial growth factor in a rat model of volume-overload heart failure. J Card Fail. 2005 Mar;11(2):152-9. |
| Groups | Approved; Investigational |
| Direct Classification | Carbazoles |
| SMILES | COC1=CC=CC=C1OCCNCC(O)COC1=CC=CC2=C1C1=CC=CC=C1N2 |
| Pathways | Carvedilol Action Pathway |
| PharmGKB | PA448817 |
| ChEMBL | CHEMBL723 |
