| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30073216 | HIV | ENSG00000147168.14 | protein_coding | IL2RG | No | No | 3561 | P31785 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | IL2RG |
|---|---|
| DrugBank ID | DB00004 |
| Drug Name | Denileukin diftitox |
| Target ID | BE0002102 |
| UniProt ID | P31785 |
| Regulation Type | |
| PubMed IDs | 15811959; 16516670; 11707860 |
| Citations | Foss F, Demierre MF, DiVenuti G: A phase-1 trial of bexarotene and denileukin diftitox in patients with relapsed or refractory cutaneous T-cell lymphoma. Blood. 2005 Jul 15;106(2):454-7. Epub 2005 Apr 5.@@Foss F: Clinical experience with denileukin diftitox (ONTAK). Semin Oncol. 2006 Feb;33(1 Suppl 3):S11-6.@@Foss FM: DAB(389)IL-2 (denileukin diftitox, ONTAK): a new fusion protein technology. Clin Lymphoma. 2000 Nov;1 Suppl 1:S27-31. |
| Groups | Approved; Investigational |
| Direct Classification | Peptides |
| SMILES | |
| Pathways | |
| PharmGKB | PA164750594 |
| ChEMBL | CHEMBL1201550 |
