| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10044531 | HBV | ENSG00000126934.15 | protein_coding | MAP2K2 | Yes | No | 5605 | P36507 |
| TVIS30004704 | HIV | ENSG00000126934.15 | protein_coding | MAP2K2 | Yes | No | 5605 | P36507 |
| TVIS30012505 | HIV | ENSG00000126934.15 | protein_coding | MAP2K2 | Yes | No | 5605 | P36507 |
| TVIS30047381 | HIV | ENSG00000126934.15 | protein_coding | MAP2K2 | Yes | No | 5605 | P36507 |
| TVIS30047382 | HIV | ENSG00000126934.15 | protein_coding | MAP2K2 | Yes | No | 5605 | P36507 |
| TVIS30047383 | HIV | ENSG00000126934.15 | protein_coding | MAP2K2 | Yes | No | 5605 | P36507 |
| TVIS30047384 | HIV | ENSG00000126934.15 | protein_coding | MAP2K2 | Yes | No | 5605 | P36507 |
| TVIS30047385 | HIV | ENSG00000126934.15 | protein_coding | MAP2K2 | Yes | No | 5605 | P36507 |
| TVIS30047386 | HIV | ENSG00000126934.15 | protein_coding | MAP2K2 | Yes | No | 5605 | P36507 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | MAP2K2 |
|---|---|
| DrugBank ID | DB06616 |
| Drug Name | Bosutinib |
| Target ID | BE0004744 |
| UniProt ID | P36507 |
| Regulation Type | inhibitor |
| PubMed IDs | 19039322 |
| Citations | Remsing Rix LL, Rix U, Colinge J, Hantschel O, Bennett KL, Stranzl T, Muller A, Baumgartner C, Valent P, Augustin M, Till JH, Superti-Furga G: Global target profile of the kinase inhibitor bosutinib in primary chronic myeloid leukemia cells. Leukemia. 2009 Mar;23(3):477-85. doi: 10.1038/leu.2008.334. Epub 2008 Nov 27. |
| Groups | Approved |
| Direct Classification | 4-aminoquinolines |
| SMILES | COC1=CC(NC2=C(C=NC3=CC(OCCCN4CCN(C)CC4)=C(OC)C=C23)C#N)=C(Cl)C=C1Cl |
| Pathways | Bosutinib Inhibition of BCR-ABL |
| PharmGKB | |
| ChEMBL | CHEMBL288441 |
