| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10049946 | HBV | ENSG00000005421.9 | protein_coding | PON1 | No | No | 5444 | P27169 |
| TVIS30081709 | HIV | ENSG00000005421.9 | protein_coding | PON1 | No | No | 5444 | P27169 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PON1 |
|---|---|
| DrugBank ID | DB00218 |
| Drug Name | Moxifloxacin |
| Target ID | BE0000930 |
| UniProt ID | P27169 |
| Regulation Type | inhibitor |
| PubMed IDs | 25519764 |
| Citations | Turkes C, Soyut H, Beydemir S: Human serum paraoxonase-1 (hPON1): in vitro inhibition effects of moxifloxacin hydrochloride, levofloxacin hemihidrate, cefepime hydrochloride, cefotaxime sodium and ceftizoxime sodium. J Enzyme Inhib Med Chem. 2015;30(4):622-8. doi: 10.3109/14756366.2014.959511. Epub 2014 Dec 18. |
| Groups | Approved; Investigational |
| Direct Classification | Quinoline carboxylic acids |
| SMILES | [H][C@]12CN(C[C@@]1([H])NCCC2)C1=C(F)C=C2C(=O)C(=CN(C3CC3)C2=C1OC)C(O)=O |
| Pathways | |
| PharmGKB | PA450555 |
| ChEMBL | CHEMBL32 |
