Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS30072688HIVENSG00000188229.6protein_codingTUBB4BNoNo10383P68371
TCGA Plot Options
Drug Information
GeneTUBB4B
DrugBank IDDB00518
Drug NameAlbendazole
Target IDBE0001367
UniProt IDP68371
Regulation Typeinhibitor
PubMed IDs11980387; 19846910; 10592235
CitationsSolana HD, Sallovitz JM, Lanusse CE, Rodriguez JA: Enantioselective binding of albendazole sulphoxide to cytosolic proteins from helminth parasites. Methods Find Exp Clin Pharmacol. 2002 Jan-Feb;24(1):7-13.@@Chu SW, Badar S, Morris DL, Pourgholami MH: Potent inhibition of tubulin polymerisation and proliferation of paclitaxel-resistant 1A9PTX22 human ovarian cancer cells by albendazole. Anticancer Res. 2009 Oct;29(10):3791-6.@@Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
GroupsApproved; Vet_approved
Direct Classification2-benzimidazolylcarbamic acid esters
SMILESCCCSC1=CC2=C(C=C1)N=C(NC(=O)OC)N2
Pathways
PharmGKBPA164746058
ChEMBLCHEMBL1483