| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS46000426 | BKPyv | ENSG00000176105.14 | protein_coding | YES1 | Yes | No | 7525 | P07947 |
| TVIS10039389 | HBV | ENSG00000176105.14 | protein_coding | YES1 | Yes | No | 7525 | P07947 |
| TVIS30007287 | HIV | ENSG00000176105.14 | protein_coding | YES1 | Yes | No | 7525 | P07947 |
| TVIS30007288 | HIV | ENSG00000176105.14 | protein_coding | YES1 | Yes | No | 7525 | P07947 |
| TVIS20053411 | HPV | ENSG00000176105.14 | protein_coding | YES1 | Yes | No | 7525 | P07947 |
| TVIS20015749 | HPV | ENSG00000176105.14 | protein_coding | YES1 | Yes | No | 7525 | P07947 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | YES1 |
|---|---|
| DrugBank ID | DB01254 |
| Drug Name | Dasatinib |
| Target ID | BE0000840 |
| UniProt ID | P07947 |
| Regulation Type | inhibitor |
| PubMed IDs | 16507911; 17541990; 20072833 |
| Citations | Trevino JG, Summy JM, Lesslie DP, Parikh NU, Hong DS, Lee FY, Donato NJ, Abbruzzese JL, Baker CH, Gallick GE: Inhibition of SRC expression and activity inhibits tumor progression and metastasis of human pancreatic adenocarcinoma cells in an orthotopic nude mouse model. Am J Pathol. 2006 Mar;168(3):962-72.@@Margutti S, Laufer SA: Are MAP kinases drug targets? Yes, but difficult ones. ChemMedChem. 2007 Aug;2(8):1116-40.@@Lindauer M, Hochhaus A: Dasatinib. Recent Results Cancer Res. 2010;184:83-102. doi: 10.1007/978-3-642-01222-8_7. |
| Groups | Approved; Investigational |
| Direct Classification | Aromatic anilides |
| SMILES | CC1=NC(NC2=NC=C(S2)C(=O)NC2=C(C)C=CC=C2Cl)=CC(=N1)N1CCN(CCO)CC1 |
| Pathways | Dasatinib Inhibition of BCR-ABL |
| PharmGKB | PA162372878 |
| ChEMBL | CHEMBL1421 |
