Loading

Cell View

Cell Information

  glioblastoma [None]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [None]

Displaying 111-120 of 120 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395955Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH31_G05glioblastoma [None]
GSE57872GSM1395957Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH31_G07glioblastoma [None]
GSE57872GSM1395964Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH31_H02glioblastoma [None]
GSE57872GSM1395966Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH31_H04glioblastoma [None]
GSE57872GSM1395967Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH31_H05glioblastoma [None]
GSE57872GSM1395969Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH31_H07glioblastoma [None]
GSE57872GSM1395970Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH31_H08glioblastoma [None]
GSE57872GSM1395971Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH31_H09glioblastoma [None]
GSE57872GSM1395972Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH31_H10glioblastoma [None]
GSE57872GSM1395974Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH31_H12glioblastoma [None]

Gene rank in glioblastoma [None]

Displaying 81-90 of 5942 results.
Rank orderGene SymbolEnsembl ID
81PTNENSG00000105894
82HNRNPA1ENSG00000135486
83RPL7ENSG00000147604
84CNBPENSG00000169714
85SPARCL1ENSG00000152583
86TROVE2ENSG00000116747
87NPM1ENSG00000181163
88ANXA2ENSG00000182718
89TNCENSG00000041982
90RPL8ENSG00000161016