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  zygote (2PN)-bad

Overall DesignWe sequenced the transcriptomes of 22 human zygotes (2PN stage) embryos, of which 11 were predicted nonviable and 11 were predicted viable. We excluded 5 which had no siblings in this data set. From the remaining 17 embryos, we analyzed the set of genes that was differentially expressed between those predicted viable and those predicted nonviable.
SummaryWe sorted 2PN stage human embryos by predicted viability using a noninvasive measurement we previously developed. We then performed RNA-seq on each embryo (which was a single cell) and looked for differences in expression between viable and nonviable embryos.
Dataset viewGSE65481
PMID26904963

Samples in zygote (2PN)-bad

Displaying 11-11 of 11 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE65481GSM1598286Illumina HiSeq 2000Homo sapiensS5zygote (2PN)-bad

Gene rank in zygote (2PN)-bad

Displaying 231-240 of 19195 results.
Rank orderGene SymbolEnsembl ID
231KIAA1551ENSG00000174718
232RPS24ENSG00000138326
233THUMPD1ENSG00000066654
234MTF2ENSG00000143033
235TPRXLENSG00000180438
236NEDD1ENSG00000139350
237RPS4XENSG00000198034
238IQUBENSG00000164675
239CCT8ENSG00000156261
240TBPL1ENSG00000028839