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  zygote (2PN)-bad

Overall DesignWe sequenced the transcriptomes of 22 human zygotes (2PN stage) embryos, of which 11 were predicted nonviable and 11 were predicted viable. We excluded 5 which had no siblings in this data set. From the remaining 17 embryos, we analyzed the set of genes that was differentially expressed between those predicted viable and those predicted nonviable.
SummaryWe sorted 2PN stage human embryos by predicted viability using a noninvasive measurement we previously developed. We then performed RNA-seq on each embryo (which was a single cell) and looked for differences in expression between viable and nonviable embryos.
Dataset viewGSE65481
PMID26904963

Samples in zygote (2PN)-bad

Displaying 11-11 of 11 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE65481GSM1598286Illumina HiSeq 2000Homo sapiensS5zygote (2PN)-bad

Gene rank in zygote (2PN)-bad

Displaying 281-290 of 19195 results.
Rank orderGene SymbolEnsembl ID
281PPP6CENSG00000119414
282FAM214AENSG00000047346
283RAD21ENSG00000164754
284TTKENSG00000112742
285PAK1IP1ENSG00000111845
286KDM1BENSG00000165097
287SGOL2
288SMARCA2ENSG00000080503
289TNRC6BENSG00000100354
290SLC3A1ENSG00000138079