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  glioblastoma [Cla]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Cla]

Displaying 11-20 of 45 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395650Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_E12glioblastoma [Cla]
GSE57872GSM1395783Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_A01glioblastoma [Cla]
GSE57872GSM1395788Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_A06glioblastoma [Cla]
GSE57872GSM1395789Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_A07glioblastoma [Cla]
GSE57872GSM1395791Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_A09glioblastoma [Cla]
GSE57872GSM1395799Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_B05glioblastoma [Cla]
GSE57872GSM1395800Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_B06glioblastoma [Cla]
GSE57872GSM1395802Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_B08glioblastoma [Cla]
GSE57872GSM1395811Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_C05glioblastoma [Cla]
GSE57872GSM1395813Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_C07glioblastoma [Cla]

Gene rank in glioblastoma [Cla]

Displaying 5771-5780 of 5942 results.
Rank orderGene SymbolEnsembl ID
5771C10orf10ENSG00000165507
5772PIRTENSG00000233670
5773LIPAENSG00000107798
5774CADPSENSG00000163618
5775GNAI1ENSG00000127955
5776SCN9AENSG00000169432
5777LEF1ENSG00000138795
5778TOR3AENSG00000186283
5779PGRMC2ENSG00000164040
5780FBXO39ENSG00000177294