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  glioblastoma [Cla]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Cla]

Displaying 11-20 of 45 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395864Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_G10glioblastoma [Cla]
GSE57872GSM1395862Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_G08glioblastoma [Cla]
GSE57872GSM1395853Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_F11glioblastoma [Cla]
GSE57872GSM1395845Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_F03glioblastoma [Cla]
GSE57872GSM1395843Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_F01glioblastoma [Cla]
GSE57872GSM1395842Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_E12glioblastoma [Cla]
GSE57872GSM1395838Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_E08glioblastoma [Cla]
GSE57872GSM1395831Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_E01glioblastoma [Cla]
GSE57872GSM1395830Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_D12glioblastoma [Cla]
GSE57872GSM1395828Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_D10glioblastoma [Cla]

Gene rank in glioblastoma [Cla]

Displaying 161-170 of 5942 results.
Rank orderGene SymbolEnsembl ID
161EIF4A2ENSG00000156976
162RPL4ENSG00000174444
163NASPENSG00000132780
164HIF1AENSG00000100644
165CHD9ENSG00000177200
166AP2M1ENSG00000161203
167LAPTM4AENSG00000068697
168ZFRENSG00000056097
169DAZAP2ENSG00000183283
170GSTP1ENSG00000084207