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  glioblastoma [Cla]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Cla]

Displaying 11-20 of 45 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395558Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_F04glioblastoma [Cla]
GSE57872GSM1395816Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_C10glioblastoma [Cla]
GSE57872GSM1395818Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_C12glioblastoma [Cla]
GSE57872GSM1395821Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_D03glioblastoma [Cla]
GSE57872GSM1395822Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_D04glioblastoma [Cla]
GSE57872GSM1395567Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_G01glioblastoma [Cla]
GSE57872GSM1395824Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_D06glioblastoma [Cla]
GSE57872GSM1395828Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_D10glioblastoma [Cla]
GSE57872GSM1395830Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_D12glioblastoma [Cla]
GSE57872GSM1395831Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_E01glioblastoma [Cla]

Gene rank in glioblastoma [Cla]

Displaying 5801-5810 of 5942 results.
Rank orderGene SymbolEnsembl ID
5801PCOLCE2ENSG00000163710
5802OR7E37PENSG00000215480
5803FGF9ENSG00000102678
5804ZNF132ENSG00000131849
5805UBQLNLENSG00000175518
5806FBLN5ENSG00000140092
5807SLC17A8ENSG00000179520
5808TREM1ENSG00000124731
5809AKAP8LENSG00000011243
5810FOCADENSG00000188352