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  glioblastoma [Pro+Cla]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Pro+Cla]

Displaying 11-20 of 20 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395859Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_G05glioblastoma [Pro+Cla]
GSE57872GSM1395861Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_G07glioblastoma [Pro+Cla]
GSE57872GSM1395401Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_A03glioblastoma [Pro+Cla]
GSE57872GSM1395403Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_A05glioblastoma [Pro+Cla]
GSE57872GSM1395411Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_B01glioblastoma [Pro+Cla]
GSE57872GSM1395425Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_C03glioblastoma [Pro+Cla]
GSE57872GSM1395434Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_C12glioblastoma [Pro+Cla]
GSE57872GSM1395435Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_D01glioblastoma [Pro+Cla]
GSE57872GSM1395450Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_E04glioblastoma [Pro+Cla]
GSE57872GSM1395468Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_F10glioblastoma [Pro+Cla]

Gene rank in glioblastoma [Pro+Cla]

Displaying 5821-5830 of 5942 results.
Rank orderGene SymbolEnsembl ID
5821THOC5ENSG00000100296
5822HIST1H1CENSG00000187837
5823ZNF12ENSG00000164631
5824SH3BGRL2ENSG00000198478
5825USP46ENSG00000109189
5826CD68ENSG00000129226
5827DCNENSG00000011465
5828MYO1GENSG00000136286
5829AENENSG00000181026
5830ASS1ENSG00000130707