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  glioblastoma [None]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [None]

Displaying 11-20 of 120 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395556Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_F02glioblastoma [None]
GSE57872GSM1395812Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_C06glioblastoma [None]
GSE57872GSM1395819Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_D01glioblastoma [None]
GSE57872GSM1395820Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_D02glioblastoma [None]
GSE57872GSM1395827Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_D09glioblastoma [None]
GSE57872GSM1395574Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_G08glioblastoma [None]
GSE57872GSM1395575Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_G09glioblastoma [None]
GSE57872GSM1395576Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_G10glioblastoma [None]
GSE57872GSM1395579Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_H01glioblastoma [None]
GSE57872GSM1395582Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_H04glioblastoma [None]

Gene rank in glioblastoma [None]

Displaying 151-160 of 5942 results.
Rank orderGene SymbolEnsembl ID
151LGALS3BPENSG00000108679
152SF3B1ENSG00000115524
153SERINC1ENSG00000111897
154EIF3IENSG00000084623
155SARSENSG00000031698
156HSPD1ENSG00000144381
157PMP2ENSG00000147588
158ERGIC3ENSG00000125991
159XRCC6ENSG00000196419
160BNIP3LENSG00000104765