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  glioblastoma [Pro+Cla]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Pro+Cla]

Displaying 11-20 of 20 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395859Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_G05glioblastoma [Pro+Cla]
GSE57872GSM1395861Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_G07glioblastoma [Pro+Cla]
GSE57872GSM1395401Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_A03glioblastoma [Pro+Cla]
GSE57872GSM1395403Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_A05glioblastoma [Pro+Cla]
GSE57872GSM1395411Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_B01glioblastoma [Pro+Cla]
GSE57872GSM1395425Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_C03glioblastoma [Pro+Cla]
GSE57872GSM1395434Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_C12glioblastoma [Pro+Cla]
GSE57872GSM1395435Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_D01glioblastoma [Pro+Cla]
GSE57872GSM1395450Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_E04glioblastoma [Pro+Cla]
GSE57872GSM1395468Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_F10glioblastoma [Pro+Cla]

Gene rank in glioblastoma [Pro+Cla]

Displaying 151-160 of 5942 results.
Rank orderGene SymbolEnsembl ID
151YWHAEENSG00000108953
152SNORD73AENSG00000208797
153EIF3CENSG00000184110
154SSR1ENSG00000124783
155MAPK1IP1LENSG00000168175
156WSB1ENSG00000109046
157RPL4ENSG00000174444
158TCF12ENSG00000140262
159AIF1LENSG00000126878
160IDH1ENSG00000138413