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  zygote (2PN)-good

Overall DesignWe sequenced the transcriptomes of 22 human zygotes (2PN stage) embryos, of which 11 were predicted nonviable and 11 were predicted viable. We excluded 5 which had no siblings in this data set. From the remaining 17 embryos, we analyzed the set of genes that was differentially expressed between those predicted viable and those predicted nonviable.
SummaryWe sorted 2PN stage human embryos by predicted viability using a noninvasive measurement we previously developed. We then performed RNA-seq on each embryo (which was a single cell) and looked for differences in expression between viable and nonviable embryos.
Dataset viewGSE65481
PMID26904963

Samples in zygote (2PN)-good

Displaying 11-11 of 11 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE65481GSM1598302Illumina HiSeq 2000Homo sapiensS21zygote (2PN)-good

Gene rank in zygote (2PN)-good

Displaying 201-210 of 19195 results.
Rank orderGene SymbolEnsembl ID
201YWHAQENSG00000134308
202GINS2ENSG00000131153
203EIF2AENSG00000144895
204MED13ENSG00000108510
205BCL2L10ENSG00000137875
206ETFAENSG00000140374
207KIAA1551ENSG00000174718
208TUBBP5ENSG00000159247
209NEK1ENSG00000137601
210NOP10ENSG00000182117