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  glioblastoma [Mes]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Mes]

Displaying 11-20 of 101 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395829Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_D11glioblastoma [Mes]
GSE57872GSM1395591Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_A01glioblastoma [Mes]
GSE57872GSM1395592Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_A02glioblastoma [Mes]
GSE57872GSM1395595Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_A05glioblastoma [Mes]
GSE57872GSM1395852Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_F10glioblastoma [Mes]
GSE57872GSM1395597Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_A07glioblastoma [Mes]
GSE57872GSM1395598Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_A08glioblastoma [Mes]
GSE57872GSM1395600Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_A10glioblastoma [Mes]
GSE57872GSM1395602Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_A12glioblastoma [Mes]
GSE57872GSM1395858Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_G04glioblastoma [Mes]

Gene rank in glioblastoma [Mes]

Displaying 311-320 of 5942 results.
Rank orderGene SymbolEnsembl ID
311PSMC2ENSG00000161057
312ZKSCAN1ENSG00000106261
313DNAJA1ENSG00000086061
314PUF60ENSG00000179950
315PRPF8ENSG00000174231
316PLEKHB2ENSG00000115762
317COPB1ENSG00000129083
318SF3B3ENSG00000189091
319TTC3ENSG00000182670
320PEX19ENSG00000162735