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  glioblastoma [Neu+Mes]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Neu+Mes]

Displaying 11-19 of 19 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395694Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_A08glioblastoma [Neu+Mes]
GSE57872GSM1395698Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_A12glioblastoma [Neu+Mes]
GSE57872GSM1395700Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_B02glioblastoma [Neu+Mes]
GSE57872GSM1395708Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_B10glioblastoma [Neu+Mes]
GSE57872GSM1395722Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_C12glioblastoma [Neu+Mes]
GSE57872GSM1395731Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_D09glioblastoma [Neu+Mes]
GSE57872GSM1395732Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_D10glioblastoma [Neu+Mes]
GSE57872GSM1395752Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_F06glioblastoma [Neu+Mes]
GSE57872GSM1395761Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_G03glioblastoma [Neu+Mes]

Gene rank in glioblastoma [Neu+Mes]

Displaying 111-120 of 5942 results.
Rank orderGene SymbolEnsembl ID
111CSDE1ENSG00000009307
112RPL8ENSG00000161016
113HNRNPCENSG00000092199
114PPP2R1AENSG00000105568
115TROVE2ENSG00000116747
116ATP5A1ENSG00000152234
117ERGIC3ENSG00000125991
118HNRNPKENSG00000165119
119MAPK1IP1LENSG00000168175
120MATR3ENSG00000015479