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  glioblastoma [Neu+Mes]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Neu+Mes]

Displaying 11-19 of 19 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395698Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_A12glioblastoma [Neu+Mes]
GSE57872GSM1395700Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_B02glioblastoma [Neu+Mes]
GSE57872GSM1395708Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_B10glioblastoma [Neu+Mes]
GSE57872GSM1395722Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_C12glioblastoma [Neu+Mes]
GSE57872GSM1395731Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_D09glioblastoma [Neu+Mes]
GSE57872GSM1395732Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_D10glioblastoma [Neu+Mes]
GSE57872GSM1395752Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_F06glioblastoma [Neu+Mes]
GSE57872GSM1395761Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_G03glioblastoma [Neu+Mes]
GSE57872GSM1395773Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_H03glioblastoma [Neu+Mes]

Gene rank in glioblastoma [Neu+Mes]

Displaying 161-170 of 5942 results.
Rank orderGene SymbolEnsembl ID
161PSMC2ENSG00000161057
162TIMP1ENSG00000102265
163CLDND1ENSG00000080822
164CNBPENSG00000169714
165LAPTM4AENSG00000068697
166DDX3XENSG00000215301
167CD59ENSG00000085063
168PIGTENSG00000124155
169SERPINA3ENSG00000196136
170ARID5BENSG00000150347