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  glioblastoma [Neu+Mes]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Neu+Mes]

Displaying 11-19 of 19 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395698Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_A12glioblastoma [Neu+Mes]
GSE57872GSM1395700Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_B02glioblastoma [Neu+Mes]
GSE57872GSM1395708Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_B10glioblastoma [Neu+Mes]
GSE57872GSM1395722Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_C12glioblastoma [Neu+Mes]
GSE57872GSM1395731Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_D09glioblastoma [Neu+Mes]
GSE57872GSM1395732Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_D10glioblastoma [Neu+Mes]
GSE57872GSM1395752Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_F06glioblastoma [Neu+Mes]
GSE57872GSM1395761Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_G03glioblastoma [Neu+Mes]
GSE57872GSM1395773Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_H03glioblastoma [Neu+Mes]

Gene rank in glioblastoma [Neu+Mes]

Displaying 181-190 of 5942 results.
Rank orderGene SymbolEnsembl ID
181LIMA1ENSG00000050405
182DTNAENSG00000134769
183PTNENSG00000105894
184COPB1ENSG00000129083
185HSPA9ENSG00000113013
186MAPRE1ENSG00000101367
187DBIENSG00000155368
188NGFRAP1
189MDH2ENSG00000146701
190RBBP4ENSG00000162521