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  glioblastoma [Pro]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Pro]

Displaying 11-20 of 88 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395454Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_E08glioblastoma [Pro]
GSE57872GSM1395456Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_E10glioblastoma [Pro]
GSE57872GSM1395460Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_F02glioblastoma [Pro]
GSE57872GSM1395463Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_F05glioblastoma [Pro]
GSE57872GSM1395466Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_F08glioblastoma [Pro]
GSE57872GSM1395467Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_F09glioblastoma [Pro]
GSE57872GSM1395469Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_F11glioblastoma [Pro]
GSE57872GSM1395470Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_F12glioblastoma [Pro]
GSE57872GSM1395473Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_G03glioblastoma [Pro]
GSE57872GSM1395483Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_H01glioblastoma [Pro]

Gene rank in glioblastoma [Pro]

Displaying 5851-5860 of 5942 results.
Rank orderGene SymbolEnsembl ID
5851PCGF6ENSG00000156374
5852CRYGSENSG00000213139
5853HSPA2ENSG00000126803
5854KIF20AENSG00000112984
5855APLNRENSG00000134817
5856NRP2ENSG00000118257
5857ITGA5ENSG00000161638
5858ELTD1
5859MTTPENSG00000138823
5860FGF9ENSG00000102678