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  glioblastoma [Neu+Mes]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Neu+Mes]

Displaying 11-19 of 19 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395698Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_A12glioblastoma [Neu+Mes]
GSE57872GSM1395700Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_B02glioblastoma [Neu+Mes]
GSE57872GSM1395708Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_B10glioblastoma [Neu+Mes]
GSE57872GSM1395722Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_C12glioblastoma [Neu+Mes]
GSE57872GSM1395731Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_D09glioblastoma [Neu+Mes]
GSE57872GSM1395732Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_D10glioblastoma [Neu+Mes]
GSE57872GSM1395752Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_F06glioblastoma [Neu+Mes]
GSE57872GSM1395761Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_G03glioblastoma [Neu+Mes]
GSE57872GSM1395773Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_H03glioblastoma [Neu+Mes]

Gene rank in glioblastoma [Neu+Mes]

Displaying 81-90 of 5942 results.
Rank orderGene SymbolEnsembl ID
81PPIAENSG00000196262
82EGR1ENSG00000120738
83PPT1ENSG00000131238
84MAGED1ENSG00000179222
85LDHBENSG00000111716
86DSTENSG00000151914
87HNRNPA1ENSG00000135486
88SPP1ENSG00000118785
89CTTNENSG00000085733
90SOD2ENSG00000112096