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  glioblastoma [Pro]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Pro]

Displaying 21-30 of 88 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395484Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_H02glioblastoma [Pro]
GSE57872GSM1395487Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_H05glioblastoma [Pro]
GSE57872GSM1395489Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_H07glioblastoma [Pro]
GSE57872GSM1395490Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_H08glioblastoma [Pro]
GSE57872GSM1395494Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_H12glioblastoma [Pro]
GSE57872GSM1395495Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_A01glioblastoma [Pro]
GSE57872GSM1395497Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_A03glioblastoma [Pro]
GSE57872GSM1395498Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_A04glioblastoma [Pro]
GSE57872GSM1395499Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_A05glioblastoma [Pro]
GSE57872GSM1395500Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_A06glioblastoma [Pro]

Gene rank in glioblastoma [Pro]

Displaying 121-130 of 5942 results.
Rank orderGene SymbolEnsembl ID
121NDUFA4ENSG00000189043
122RPL4ENSG00000174444
123PPP1CBENSG00000213639
124ANXA5ENSG00000164111
125RPS14ENSG00000164587
126YWHAEENSG00000108953
127COPS6ENSG00000168090
128DDOSTENSG00000244038
129DDX3XENSG00000215301
130WSB1ENSG00000109046